USDA Approves Import of Live Avian Metapneumovirus Vaccine: A Milestone for U.S. Poultry Industry

The U.S. Department of Agriculture (USDA) recently approved the importation of a live avian metapneumovirus (aMPV) vaccine, a crucial step toward combating a widespread threat to the poultry industry. Developed by Vaxxinova Italy, the vaccine targets Swollen Head Syndrome, an alternative name for aMPV. Set to be available in the U.S. by early 2025, this development brings renewed hope to poultry producers grappling with the disease’s devastating effects.

The Significance of the USDA Approval

Brian Harberts, Managing Director at Vaxxinova, highlighted the significance of this milestone:

 

The USDA’s decision marks an important milestone for the U.S. turkey and poultry industry, which has been devastated by aMPV. Through collaboration with organizations like the National Turkey Federation, poultry producers, and the USDA, Vaxxinova US can now provide the same vaccine that has served European producers for over 20 years.”

This approval aligns with efforts to mitigate the economic and productivity losses caused by aMPV, especially in high-production states.

 

Understanding aMPV

Avian metapneumovirus (aMPV) is a highly contagious respiratory disease affecting all species of commercial poultry, as well as some wild birds. The disease is known to:

Cause respiratory distress, characterized by coughing, nasal discharge, and swollen sinuses.

Result in significant drops in egg production and egg quality among layers, broilers, and turkey breeder hens.

The virus is categorized into subtypes A to D, with subtypes A and B being most prevalent in the U.S. While aMPV is not a notifiable disease for the USDA, experts believe it is likely present across most poultry-producing states, making proactive measures essential.

Economic Impacts on the Poultry Industry

The economic impact of aMPV on the U.S. poultry industry is profound. Losses stem from:

1. Reduced productivity in turkey and chicken flocks.

2. Higher mortality rates during outbreaks

3. Increased veterinary and management costs associated with controlling the disease.

The introduction of a reliable vaccine has the potential to significantly curb these losses, making it a game-changer for farmers and poultry businesses.

A Second Vaccine Approved

This live vaccine marks the second USDA approval of an aMPV vaccine in recent months. In October 2024, the agency approved a killed vaccine against aMPV subtype B, developed by Boehringer-Ingelheim. Together, these vaccines offer poultry producers more tools to protect their flocks.

Industry Response: National Turkey Federation

The National Turkey Federation (NTF) has long advocated for aMPV vaccine importation. Following the USDA’s approval, NTF released a statement:

The National Turkey Federation welcomes the USDA’s approval of a commercial modified live avian metapneumovirus (aMPV) vaccine. This development underscores our industry’s commitment to ensuring the health and productivity of our nation’s commercial turkey population. We encourage the USDA to continue its work on additional vaccine imports and development.”

This endorsement reflects the broader industry’s recognition of vaccines as a cornerstone of poultry health management.

Benefits of Live Vaccines

Live vaccines, like the one developed by Vaxxinova, are known for their efficacy in combating respiratory diseases. Key advantages include:

Rapid immune response compared to killed vaccines.

Ease of administration through drinking water or aerosol spraying.

Potential for long-term immunity, reducing the frequency of outbreaks.

These features make live vaccines an attractive option for large-scale poultry operations.

Challenges in Combating aMPV

Despite advancements, challenges remain in controlling aMPV:

1. Detection Gaps: Since aMPV is not a reportable disease, there is limited data on its prevalence.

2. Biosecurity Measures: Many farms lack stringent biosecurity protocols, increasing the risk of disease spread.

3. Vaccine Distribution: Ensuring timely distribution of vaccines to high-risk areas is critical.

Producers must complement vaccination efforts with robust farm management practices to maximize disease control.

A Glimpse Into the Future

The USDA’s approval of this vaccine represents a proactive approach to safeguarding the U.S. poultry industry. With aMPV affecting productivity and profitability, this development is expected to benefit not only large-scale producers but also small-scale farmers who depend on poultry for their livelihoods.

The vaccine’s availability in 2025 will likely set a new standard for respiratory disease management, fostering a healthier and more sustainable poultry sector

Conclusion

The approval of Vaxxinova’s live aMPV vaccine by the USDA is a landmark moment for the U.S. poultry industry. As farmers prepare to integrate this vaccine into their disease management strategies, the industry is poised for improved resilience against aMPV outbreaks. Coupled with continued research and collaboration, this development underscores a commitment to a stronger, more productive poultry sector in the U.S.

For farmers, stakeholders, and policymakers, this marks a step forward in addressing the challenges of poultry health in a competitive and demanding market.

 

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